"What is widely unknown about mushrooms is the way that it affects each individual," he said. "And this iswhat needs to be known and what needs to be documented so that we can go forward with regulating fungus properly." If you are looking psilocybin-assisted therapy for a solution to preserve your magic mushrooms for a long time, then you can dry them and store them in a cool, dark, and dry place for up to 2-3 years (maybe even longer). The only risks you could run are any insect attacks or loss of power due to excessive exposure to light, humidity, and heat. This preservation process works very well as it eliminates the excess internal humidity and, consequently, the mushrooms interrupt their decomposition phase. If you smoke shrooms mixed with tobacco, you tack on all the risks associated with that, too.